What clinical metabolomics will bring to the medicine of tomorrow

The purpose of this review is to explore how clinical metabolomics could help physicians in the future. recent advent medical genomics brings new and interesting technological tools measure genetic predispositions a disease. But will allow us go even further by linking patient’s pathological phenotype with gene expression defects metabolic disorders. It context that chemist must adapt be force proposal meet these health challenges. He clinician mastering innovative tools, order participate implementation studies for discovery biomarkers, but also propose assays biomarkers called “signatures,” which can composite or fingerprints, ultimately guide clinician. have them as chemistry tests. In first part, we look at some concrete examples use research projects led identification biomarker. We example trimethylamine N-oxide (or TMAO) proposed TMAO biomarker cardiovascular diseases. second see through bibliographic studies, metabolomic fingerprint useful build supervised model patient stratification. conclusion, discuss limitations currently under debate.