Wernicke like encephalopathy in a child: A reversible cause

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Wernicke like encephalopathy in a child: A reversible cause

Wernicke’s encephalopathy (WE) is the best known neurological complication of thiamine deficiency, characterized by ocular, symptoms, mental confusion and ataxia. we report herewith a male child with unusual features, suggestive of WE and with thiamine treatment, the response was dramatic.Participated in the national seminar on Consumerism in DNR College, Bvrm

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BACKGROUND Wernicke encephalopathy (WE) is a metabolic disorder of the central nervous system resulting from vitamin B(1) deficiency. The exact mechanisms underlying the pathogenesis of the lesions in WE are not completely understood. Vitamin B1 deficiency is associated with intracellular and extracellular edema by glutamate(N-methyl-D-aspartate) receptor-mediated excitotoxicity. Conventional m...

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Wernicke encephalopathy: a medical emergency.

Thiamine (vitamin B1) deficiency causing Wernicke encephalopathy occurs most frequently in people with compromised absorption (e.g., malnutrition, hyperemesis), increased metabolism (e.g., sepsis, malignancy) or increased carbohydrate intake (e.g., administration of intravenous dextrose). Guidelines from the European Federation of Neurological Societies suggest that Wernicke enceph alopathy is ...

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Wernicke ’ S Encephalopathy Revisited

Aims: A translation into English of the case history section of Carl Wernicke’s original manuscript of 1881, with a discussion on its relevance for clinicians today. Methods: A copy of Carl Wernicke’s original German text was obtained by one of the authors (CCHC) and translated into English from the old German by a professional translator. Results: The translation was subsequently agreed by nat...

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Carl Wernicke described first Wernicke encephalopathy in 1881. He reported a pathological clinical situation, which comprises a triad of symptoms with acute mental confusion, ataxia, and ophthalmoplegia. He described three patients, two with a story of high alcohol consumption and one patient with persistent vomiting that presented with progressive stupor and coma, progressing to death. After t...

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ژورنال

عنوان ژورنال: Journal of Pediatric Neurosciences

سال: 2012

ISSN: 1817-1745

DOI: 10.4103/1817-1745.102583