VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans
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چکیده
منابع مشابه
Antifungal activity of essential oils from Iranian plants against fluconazole-resistant and fluconazole-susceptible Candida albicans
Objectives: The purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (FLU)-resistant and FLU-susceptible C. albicans strains isolated from HIV positive patients with oropharyngeal candidiasis (OPC). Materials and Methods: The essential oils were obtained by hydrodistillation method from Myrtus communis (My. communis)...
متن کاملEfficacy of the clinical agent VT-1161 against fluconazole-sensitive and -resistant Candida albicans in a murine model of vaginal candidiasis.
Vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC) remain major health problems for women. VT-1161, a novel fungal CYP51 inhibitor which has potent antifungal activity against fluconazole-sensitive Candida albicans, retained its in vitro potency (MIC50 of ≤0.015 and MIC90 of 0.12 μg/ml) against 10 clinical isolates from VVC or RVVC patients resistant to fluconazole (MIC50 of 8 and MIC90 of...
متن کاملAntifungal activity of essential oils from Iranian plants against fluconazole-resistant and fluconazole-susceptible Candida albicans
OBJECTIVE The purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (FLU)-resistant and FLU-susceptible C. albicans strains isolated from HIV positive patients with oropharyngeal candidiasis (OPC). MATERIALS AND METHODS The essential oils were obtained by hydrodistillation method from Myrtus communis (My. communis),...
متن کاملantifungal activity of essential oils from iranian plants against fluconazole-resistant and fluconazole-susceptible candida albicans
objectives: the purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (flu)-resistant and flu-susceptible c. albicans strains isolated from hiv positive patients with oropharyngeal candidiasis (opc). materials and methods: the essential oils were obtained by hydrodistillation method from myrtus communis (my. communis)...
متن کاملIn vitro antifungal activity of essential oils extracted from plants against fluconazole-susceptible and -resistant Candida albicans
Backgrounds and aims: Candida albicans is more prevalent between Candida species which can cause candidal infection. Various studies have shown drug resistance among the C. albicans isolates, so it is now necessary to discover replacement treatments for the Candida infection. The aim of this study is comparison the effects of different Essential oils (EOs) against azoles-resistant and azoles-su...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2017
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkx352