Vitamin D supplementation and colorectal cancer prognosis
نویسندگان
چکیده
منابع مشابه
Vitamin D and Colorectal Cancer
In a study involving data from large, Scottish, case-control study, inverse and dose-dependent associations were found between colorectal cancer risk and total vitamin D (OR=0.80) intake according to multivariable-adjusted logistic regression models. On the other hand, no associations were found between calcium intake or vitamin D receptor variants and colorectal cancer. In addition, the author...
متن کاملEpidemiology of vitamin D and colorectal cancer.
Garland and Garland first hypothesized that better vitamin D status lowered risk of colorectal cancer in 1980. Subsequently, the relation between vitamin D status and colorectal cancer risk has been investigated in epidemiologic studies. Various approaches have been used to estimate vitamin D status, including direct measures of circulating 25(OH)vitamin D levels, surrogates or determinants of ...
متن کاملVitamin D and prevention of colorectal cancer.
BACKGROUND Inadequate photosynthesis or oral intake of Vitamin D are associated with high incidence rates of colorectal cancer, but the dose-response relationship has not been adequately studied. METHODS Dose-response gradients from observational studies of Vitamin D intake and serum 25-hydroxyvitamin D were plotted as trend lines. The point on each linear trend line corresponding to an odds ...
متن کاملSerum Vitamin D Metabolites in Colorectal Cancer Patients Receiving Cholecalciferol Supplementation: Correlation with Polymorphisms in the Vitamin D Genes
Cholecalciferol (D(3)) supplementation results in variable increases in serum 25(OH)D(3) levels, however, the influence of genetic polymorphisms on these variable responses is unclear. We measured serum 25(OH)D(3), 24,25(OH)(2)D(3), 1,25(OH)2D(3) and VDBP levels in 50 colorectal cancer (CRC) patients before and during 2,000 IU daily oral D(3) supplementation for six months and in 263 archived C...
متن کاملCalcium plus vitamin D supplementation and the risk of colorectal cancer.
BACKGROUND Higher intake of calcium and vitamin D has been associated with a reduced risk of colorectal cancer in epidemiologic studies and polyp recurrence in polyp-prevention trials. However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking. METHODS We conducted a randomized, double-blind, placebo-c...
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ژورنال
عنوان ژورنال: Medical Oncology
سال: 2019
ISSN: 1357-0560,1559-131X
DOI: 10.1007/s12032-019-1293-x