Vitamin D and skeletal health in autoimmune bullous skin diseases: a case control study

Vitamin D and skeletal health in autoimmune bullous skin diseases: a case control study

BACKGROUND The presence of hypovitaminosis D in patients with autoimmune bullous skin diseases, such as pemphigus vulgaris (PV) and bullous pemphigoid (BP), is debated. In a previous study we found an increased prevalence of vertebral fractures (VFx) and hypovitaminosis D in PV and BP patients. The present study extends the sample size of the previous one, for investigating the 25-hydroxyvitami...

Evaluation of serum Prolactin levels in patients with autoimmune blistering skin diseases: A case-control study

Background: Prolactin, a neurohormone, can act as a stimulator of immunity in a number of autoimmune diseases and its high levels have been shown in these diseases. Objective: This study was designed to discover the possible role of prolactin in autoimmune blistering skin diseases. The main goal was to compare the serum prolactin levels and the frequency of hyperprolactinemia in autoimmune skin...

New Observations in Autoimmune Bullous Skin Diseases

A cross-sectional study of clinical, histopathological and direct immmunofluorescence diagnosis in autoimmune bullous diseases

Background: Immunobullous diseases are morphologically heterogeneous and the differentiation between various subtypes is essential for proper treatment and prognosis. The aim of our study was to analyze and correlate clinical, histopathological, and immunofluorescence findings in autoimmune bullous diseases.Method: A c...

Bullous Skin Diseases: Classical Types of Autoimmune Diseases

The prototypic bullous skin diseases, pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid, are characterized by the blister formation in the skin and/or oral mucosa in combination with circulating and deposited autoantibodies reactive with (hemi)desmosomes. Koch's postulates, adapted for autoimmune diseases, were applied on these skin diseases. It appears that all adapted Koch's pos...