Vitamin D and intestinal calcium absorption

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Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women.

BACKGROUND The relative importance of vitamin D metabolites in the regulation of gut calcium absorption has not been well studied in elderly women living in an environment with abundant sunlight. OBJECTIVE The objective was to examine the determinants of active gut calcium absorption ( +/- SD: 42 +/- 11%) after an overnight fast with the use of a low (10 mg) calcium load. DESIGN One hundred...

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Serum vitamin D metabolites and intestinal calcium absorption efficiency in women.

BACKGROUND Vitamin D sufficiency may be determined by the serum concentration of 25-hydroxyvitamin D [25(OH)D] that results in maximal intestinal calcium absorption efficiency. However, some investigators questioned whether 25(OH)D concentrations above the concentrations associated with rickets or osteomalacia influence calcium absorption. OBJECTIVE We determined whether calcium absorption ef...

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Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium.

Intestinal calcium absorption assessed by a double-isotope method, decreased significantly with aging in 94 normal subjects (r = -0.22, P < 0.025). In 52 untreated patients with postmenopausal osteoporosis, calcium absorption was significantly lower than normal when either age or habitual calcium intake was used as a covariable (P < 0.001). Serum 25-hydroxyvitamin D (25-OH-D) and 1,25-dihydroxy...

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Role of vitamin D-dependent and vitamin D-independent mechanisms in absorption of food calcium.

We measured net calcium absorption and the calcium content of the digestive glands secretions in people with widely different serum concentrations of 1,25 dihydroxy vitamin D (hereafter referred to a 1,25-D). Patients with end stage renal disease on hemodialysis served as a model of human 1,25-D deficiency; they were also studied when they had abnormally high serum 1,25-D concentrations as a re...

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Intestinal absorption of vitamin D: a systematic review.

Context Vitamin D is frequently prescribed as a supplement, yet its absorption remains poorly understood. Objective This systematic review was performed to evaluate data on mechanisms involved in the intestinal absorption of vitamin D. Data Sources PubMed, Embase, and Cochrane Library databases were searched. Study Selection The following studies were included: experimental laboratory stu...

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ژورنال

عنوان ژورنال: Molecular and Cellular Endocrinology

سال: 2011

ISSN: 0303-7207

DOI: 10.1016/j.mce.2011.05.038