Vitamin C prevents DNA mutation induced by oxidative stress.
نویسندگان
چکیده
منابع مشابه
Vitamin C modulates oxidative stress-induced colitis in rats
Materials and methods: This study was conducted with rats for a period of 7 days. Group 1 intrarectally received a placebo (0.9% NaCl) and group 2 intrarectally received 2 mL of 5% acetic acid (AA) and the placebo. Group 3 intrarectally received 2 mL of 5% AA and vitamin C (100 mg/kg of body weight) via gastric gavage. Myeloperoxidase (MPO), catalase (CAT), prolidase (PRS), and arylesterase (AR...
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Reactive oxygen metabolites can pro mote carcinogenesis by damaging DNA. vi tamin C is a redox chemical with antioxi dant and pro-oxidant properties that may produce radical species depending on the presence of various conditions. Nevertheless, evidence presented herein discourages the consideration of any mutagenic or carcino genic activity of vitamin C. In contrast, it substantiates a pro...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)60112-7