Vitamin B12 and protein metabolism

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Vitamin B12 and protein metabolism.

Fat in the diet of rats. 8 39 carbon dioxide plus soya-bean oil (ratio 2: I) grew poorly, and all died during the first half of the experimental period. 4. The animals fed on a mixture of PT 006 or PT 006 plus distillate-soya-bean oil (ratio 2: I ) grew throughout the whole experimental period (36 weeks), although significantly more slowly than the controls. No neoplastic tissue was found at au...

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Relationships between Biotin and Vitamin B12. Effects of Biotin and Vitamin B12 on Folic Acid Metabolism.

1. The effects of dietary biotin compared with vitamin B(12) on the total content and on the distribution of the various folate derivatives in the liver of rats given a biotin-free diet have been studied. The effect of both vitamins on the conversion in vitro of folic acid into citrovorum factor in the same experimental conditions was also examined. 2. In biotin-treated rats as well as in vitam...

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Thiocyanate metabolism in human vitamin B12 deficiency.

Patients with subacute combined degeneration who smoked had significantly lowered plasma thiocyanate levels than control smokers, but plasma thiocyanate levels in non-smoking patients with neurological disease due to vitamin B(12) deficiency were not significantly different from control values. The results provide no support for the hypothesis that chronic cyanide intoxication is responsible fo...

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Vitamin B12 metabolism and massive-dose methyl vitamin B12 therapy in Japanese patients with multiple sclerosis.

Serum vitamin B12 levels and unsaturated vitamin B12 binding capacities were measured in 24 patients with multiple sclerosis (MS), 73 patients with other neurological disorders and 21 healthy subjects. There was no decrease in the vitamin B12 levels, however, a significant decrease in the unsaturated vitamin B12 binding capacities was observed in patients with MS when compared with other groups...

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Vitamin B12 Metabolism during Pregnancy and in Embryonic Mouse Models

Vitamin B(12) (cobalamin, Cbl) is required for cellular metabolism. It is an essential coenzyme in mammals for two reactions: the conversion of homocysteine to methionine by the enzyme methionine synthase and the conversion of methylmalonyl-CoA to succinyl-CoA by the enzyme methylmalonyl-CoA mutase. Symptoms of Cbl deficiency are hematological, neurological and cognitive, including megaloblasti...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 1956

ISSN: 0007-1145,1475-2662

DOI: 10.1079/bjn19560009