Visualizing protein–DNA interactions at the single-molecule level
نویسندگان
چکیده
منابع مشابه
Visualizing protein-DNA interactions at the single-molecule level.
Recent advancements in single-molecule methods have allowed researchers to directly observe proteins acting on their DNA targets in real-time. Single-molecule imaging of protein-DNA interactions permits detection of the dynamic behavior of individual complexes that otherwise would be obscured in ensemble experiments. The kinetics of these processes can be monitored directly, permitting identifi...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2010
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2009.10.035