Visualisation of proteome-wide ordered protein abundances in Trypanosoma brucei

Background: Trypanosoma brucei is a protozoan parasite and etiological agent of human animal African trypanosomiasis. It has complex life cycle, but the most studied cellular types are in vitro cultivated bloodstream- procyclic-forms. These correspond to replicating, mammalian host bloodstream-dwelling, slender trypomastigotes tsetse vector midgut-dwelling procyclic lifecycle stages, respectively. Several proteomics studies have reported differential abundance proteins between these vitro cultivated cell types. However, there no datasets providing protein abundance, from least abundant, within both types. Methods: We used MaxQuant software 1.6.10.4 reprocess recent large-scale experiment our laboratory extracted intensity-based quantifications bloodstream form proteomes. Results: created web interface visually explore abundances T. brucei Conclusions: The visualization tool, searchable by name(s) attribute(s), is likely be useful trypanosome research community. will allow users contextualise their interest in terms proteomes.