Visible-Light Photoredox Catalysis for the Synthesis of Fluorinated Aromatic Compounds

نویسندگان

چکیده

Fluorine-containing functional groups are important motifs influencing physical and biological properties of organic compounds. Visible-light photoredox catalysis as a powerful strategy for the activation small molecules contributed significantly to rapid progress new synthetic procedures allowing introduction fluorine atoms into substrates. In this review, we highlight distinct strategies transition metal- organic-photocatalytic fluorination arenes heteroarenes by broad range fluorinating The presented divided two groups. first group involves reactions enabling direct attachment CF3-, CnFm-, F-, CF3O-, CF3S-, SO2F- substituents various aromatic second presents tandem where formation system occurs after installation fluorine-containing on non-aromatic fragment molecule.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Photoredox catalysis with visible light.

The increasing need for more efficient synthetic methods and sustainable processes can be seen as a major driving force for new inventions; it also stimulates the creative rethinking of known concepts, which, in turn, will lead to the development of innovative chemistry. For example, starting from the challenge to mimic and understand enzymatic transformations, organocatalysis has now become an...

متن کامل

Synthesis of oxindoles via visible light photoredox catalysis.

2-Electron-withdrawing-group-substituted 2-bromoanilides can be converted to the corresponding 3,3-disubstituted oxindoles with high efficiency under visible light irradiation by using fac-Ir(ppy)(3) as the photoredox catalyst. This protocol is suitable for the synthesis of oxindoles with chloro and bromo atoms attached to the phenyl ring.

متن کامل

Visible-light photoredox catalysis in flow.

Photoredox catalysts have recently been utilized as powerful tools for synthetic chemists to exploit the energy gained by the absorption of low-energy light within the visible spectrum to initiate a variety of organic transformations. The development of methods based on the single electron transfer properties of photoredox catalysts, particularly in the last several years, has represented a par...

متن کامل

Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible-Light Photoredox Catalysis.

The radical fluoroalkylation of isocyanides with fluorinated sulfones is enabled by visible-light photoredox catalysis. A wide range of readily available mono-, di-, and trifluoromethyl heteroaryl sulfones can thus be used as efficient radical fluoroalkylation reagents under mild conditions. This method not only describes a new synthetic application of fluorinated sulfones, but also provides a ...

متن کامل

Acyl Radicals from Aromatic Carboxylic Acids by Means of Visible-Light Photoredox Catalysis

Simple and abundant carboxylic acids have been used as acyl radical precursor by means of visible-light photoredox catalysis. By the transient generation of a reactive anhydride intermediate, this redox-neutral approach offers a mild and rapid entry to high-value heterocyclic compounds without the need of UV irradiation, high temperature, high CO pressure, tin reagents, or peroxides.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Catalysts

سال: 2023

ISSN: ['2073-4344']

DOI: https://doi.org/10.3390/catal13010094