Viral Profile and Clinical Characteristic in Acute Asthma Exacerbation Patients

نویسندگان

چکیده

Background: Asthma is a heterogeneous disease characterized by chronic airway inflammation. Thevirus infection in respiratory tract will activate greater pro-inflammatory cytokines asthma patients.The enhancement of induces various clinical symptoms. This study aims toinvestigate the virus and characteristics among patients with acute exacerbation.Methods: In this study, subjects were divided into 3 groups based on exacerbation triggers.The first group triggered infection; second non-virus ILI; andthe third without any infection. Nasopharynx or throat swabs collected to detect respiratoryvirus. Virus was detected Multiplex PCR (xTAG Respiratory Viral Panel Fast V2/ LUMINEX)Results: According examination, prevalence 46.2%. Only two types ofviruses identified, which Influenza A Rhinovirus. All showeda symptom cough purulent sputum, while no from other showed similarsymptoms. PEFR % prediction higher than inRhinovirus infected-patients (210 L/min 48.6% vs 195 45%).Conclusion: Acute one most reasons came emergency ward. Themajority caused infection, it viral Clinicalsign differs according trigger, therefore use antibiotics should be avoided, unless there are signsand symptoms bacterial infections

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ژورنال

عنوان ژورنال: Indian journal of forensic medicine and toxicology

سال: 2021

ISSN: ['0973-9122', '0973-9130']

DOI: https://doi.org/10.37506/ijfmt.v15i2.14872