Viral Infections and the Neonatal Brain

Congenital Viral Infections of the Brain: Lessons Learned from Lymphocytic Choriomeningitis Virus in the Neonatal Rat

The fetal brain is highly vulnerable to teratogens, including many infectious agents. As a consequence of prenatal infection, many children suffer severe and permanent brain injury and dysfunction. Because most animal models of congenital brain infection do not strongly mirror human disease, the models are highly limited in their abilities to shed light on the pathogenesis of these diseases. Th...

Viral respiratory tract infections in the neonatal intensive care unit

Viral Infections in a Neonatal Intensive Care Unit

Background and aims: The incidence of neonatal viral infections is probably underestimated. Our objective was to assess the incidence of viral infections among hospitalized infants in a level III neonatal intensive care unit, the associated clinical manifestations and outcome. Material and methods: We conducted an observational retrospective study of patients admitted to the neonatal intensive ...

HLA-KIR Interactions and Immunity to Viral Infections

Host genetic factors play a central role in determining the clinical phenotype of human diseases. Association between two polymorphic loci in human genome, human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptors (KIRs), and genetically complex infectious disease, particularly those of viral etiology, have been historically elusive. Hence, defining the influence of genetic di...

P-53: Chronic Viral Infections and Infertility in Male

Background: The most common sexually transmitted diseases and the economic and social health problem throughout the world. However, vaccine coverage and antibiotic therapy and the development of programs to prevent and control major causes of acute and chronic diseases, pregnancy complications and infertility remains. Acute and chronic systemic viral infections can lead to infertility and perma...