منابع مشابه
Coleman of vigabatrin induced visual field defects
http://bjo.bmj.com/content/86/8/931.full.html Updated information and services can be found at: These include: References http://bjo.bmj.com/content/86/8/931.full.html#ref-list-1 This article cites 3 articles, 2 of which can be accessed free at: service Email alerting the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the box at...
متن کاملVisual field defects associated with vigabatrin therapy.
OBJECTIVE To estimate the prevalence of visual field defects in patients taking the anticonvulsant drug vigabatrin and to characterise the features of visual dysfunction found. METHODS Thirty three unselected patients attending neurology and epilepsy clinics were identified as taking vigabatrin and asked to attend for neuro-ophthalmic evaluation. A control group of 16 patients with epilepsy u...
متن کاملVigabatrin and Visual Field Defects in Pediatric Epilepsy Patients
We studied the prevalence, type and severity of vigabatrin (VGB)-attributed visual field defects (VFDs), and used these data to assess the associated risk factors in pediatric patients. Medical records were retrospectively reviewed for 67 pediatric patients who received VGB alone or in combination with other antiepileptic drugs, and who had undergone visual field examinations using a Humphrey v...
متن کاملVigabatrin-induced peripheral visual field defects in patients with refractory partial epilepsy.
PURPOSE Vigabatrin can cause retinopathy, resulting in bilateral visual field constriction. Previous analyses of results from a prospective, observational study assessing vigabatrin-induced visual field constriction (described below) employed a partially subjective interpretation of static perimetery. To affirm these previous findings through more objective, quantitative methodology, we now rep...
متن کاملGABA and the ornithineδ-aminotransferase gene in vigabatrin-associated visual field defects
Vigabatrin use in some epilepsy patients has been associated with persistent visual field constriction and retinal dysfunction. The mechanism is unknown, but could be related to vigabatrin, chronic epilepsy, GABA toxicity, or the effect of a metabolite in combination with a predisposing genotype. The aim of this study was to investigate the latter two hypotheses. Levels of brain gamma-aminobuty...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1998
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-12-2-7