Viewing cancer genes from co-evolving gene modules
نویسندگان
چکیده
منابع مشابه
Viewing cancer genes from co-evolving gene modules
MOTIVATION Studying the evolutionary conservation of cancer genes can improve our understanding of the genetic basis of human cancers. Functionally related proteins encoded by genes tend to interact with each other in a modular fashion, which may affect both the mode and tempo of their evolution. RESULTS In the human PPI network, we searched for subnetworks within each of which all proteins h...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2010
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btq055