Veterinary vaccine production using bioreactors: scale up study from laboratory and pd up to commercial production

Veterinary vaccine production using bioreactors: scale up study from laboratory and pd up to commercial production

Background Vaccination has proven itself as the most effective tool to control and prevent the disease and to facilitate the safe trade of live animals. Viral vaccine manufacturing processes present some specific constraints as compared to other biotech products linked to the cell substrate used and to the viral production. Multiple cell lines are used for productions such as VERO, MDCK, MRC5, ...

Production Scale Up of Nanofibers: A Review

A Scaling-up Synthesis from Laboratory Scale to Pilot Scale and to near Commercial Scale for Paste-Glue Production

This paper concerns on developing a synthesis method of paste-glue production for gummed tape using a corn-based starch as an alternative feedstock from laboratory-scale to pilot-scale and to near commercial scale. Basically, two methods of synthesis were developed to produce paste-glue in laboratory scale. Based on the two methods, we then scale-up the earlier laboratory scale data to pilot-sc...

Fast Scale up Using Microreactors: from Microscale to Production

In this study, the excellent scalability of flow chemistry was shown. Selective formation of mono-bromoketones was chosen as a model reaction. In a full multivariate optimization experiment, 60 different settings for reaction parameters such as temperature and reaction time were screened, requiring only small amounts of chemicals. A mathematical model of the data was obtained and an optimum set...

production scale up of nanofibers: a review

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