Very late recurrence of Diethylstilbestrol - related clear cell carcinoma of the cervix: case report

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Very late recurrence of Diethylstilbestrol - related clear cell carcinoma of the cervix: case report

Clear cell adenocarcinoma of the cervix is a rare tumor of the lower genital tract. It has been described in young women with a history of intra uterine exposure to diethylstilbestrol. This tumor is characterized by a greater tendency for late recurrences. In this article, we report the case of one exposed-patient who developed recurrence as liver metastases, 24 years after the initial treatmen...

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Primary Clear Cell Carcinoma with no Diethylstilbestrol Exposure; Case Series

One of the rare neoplasms of cervix uteri and vagina is clear cell carcinoma; mostly in patients with a positive past medical history of intrauterine diethylstilbestrol (DES) exposure which reveals the importance of other unknown risk factors of gynecologic neoplasms. 2 Asian women referred to the gynecology-oncology department. The first one came with a complaint of prolonged vaginal discharge...

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Non-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review

Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-...

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Hyalinizing Clear Cell Carcinoma of Buccal Vestibule: A Rare Case

Hyalinizying clear cell carcinoma is a rare tumor which affects women more than men and is more common in minor salivary glands. The purpose of this paper was to describe a case of hyalinizing clear cell carcinoma of buccal vestibule in a 55-year-old woman. It is important to differentiate this neoplasm from other tumors with clear cell features because of their differences in treatment and cli...

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ژورنال

عنوان ژورنال: Gynecologic Oncology Research and Practice

سال: 2015

ISSN: 2053-6844

DOI: 10.1186/s40661-015-0010-5