Versatility of the Angiotensin II Type 1 Receptor
نویسندگان
چکیده
منابع مشابه
Versatility of the angiotensin II type 1 receptor.
This issue of Circulation Research includes 3 interesting studies that represent new concepts of AT1 receptor–mediated cell signaling in the cardiovascular system, which is currently of intense interest. The AT1 receptor mediates many important cardiovascular responses, including vasoconstriction, vascular and cardiac remodeling (cell proliferation, hypertrophy, and production of extracellular ...
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In the 1970s, a series of observations demonstrated that angiotensin II has deleterious effects on the heart and kidney and that patients with high levels of plasma renin activity are at a higher risk of developing stroke or myocardial infarction than those with low plasma renin activity.1,2 Thereafter, the development of pharmacological probes that block the renin-angiotensin system helped def...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1998
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.82.12.1352