منابع مشابه
Dystroglycan Versatility
cytoskeleton, thus stabilizing the muscle as it alternately Martin E. Hemler Dana-Farber Cancer Institute contracts and relaxes. In particular, the a-dystroglycan protein binds to the extracellular matrix protein Boston, Massachusetts 02115 laminin-2, while b-dystroglycan spans the membrane and links directly to dystrophin, and other cytoskeletal proteins in the dystrophin family (Figure 1A). T...
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Mutations in PSEN1 and PSEN2 genes, encoding presenilin 1 (PS1) and presenilin 2 (PS2), respectively, cause autosomal-dominant Alzheimer’s disease (ADAD) (1, 2). The precise mechanism by which PS1 mutations lead to AD is under active investigation. Multiple theories have been suggested to explain the role of PS1 and PS2 mutations on AD pathogenesis, including the effects on γ-secretase activity...
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MicroRNAs (miRNAs) are short single-stranded RNA molecules that regulate gene expression. MiRNAs originate from large primary (pri) and precursor (pre) transcripts that undergo various processing steps along their biogenesis pathway till they reach their mature and functional form. It is not clear, however, whether all miRNAs are processed similarly. Here we show that the ratio between pre-miRN...
متن کاملVersatility of microbial proteases
Proteases or peptidases constitute the largest group of enzymes in bio-industry with a long array of uses. They play an invincible role in industrial biotechnology, especially in detergent, food and pharmaceutical arena. This focused review encompasses an overview on alkaline proteases, mainly of microbial sources in a handy module. Following an introduction and general classification with evol...
متن کاملVersatility of V-Y Flap in Gluteal Area
BACKGROUND Lesions in perineal area are common. The usual treatment is coverage by skin graft and flaps which may be local, pedicled or free types. In this paper V-Y flaps were used to cover the defects. METHODS V-Y flaps were used in the gluteal area in 15 patients. Lesions were due to different causes. RESULTS Of 15 patients, 11 were males and 4 were females. Their ages ranged from 3...
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ژورنال
عنوان ژورنال: Mapana - Journal of Sciences
سال: 2005
ISSN: 0975-3303,0975-3303
DOI: 10.12723/mjs.7.9