Versatile Polymer Nanocapsules via Redox Competition

Redox-responsive nanocapsules for intracellular protein delivery.

Direct delivery of proteins to the cytosol of cells holds tremendous potential in biological and medical applications. Engineering vehicles for escorting proteins to the cytosol in a controlled release fashion has thus generated considerable interest. We report here the preparation of redox-responsive single-protein nanocapsules for intracellular protein delivery. Through in situ interfacial po...

Polymer-based nanocapsules for drug delivery.

A review of the state of knowledge on nanocapsules prepared from preformed polymers as active substances carriers is presented. This entails a general review of the different preparation methods: nanoprecipitation, emulsion-diffusion, double emulsification, emulsion-coacervation, polymer-coating and layer-by-layer, from the point of view of the methodological and mechanistic aspects involved, e...

A versatile strategy for uniform hybrid nanoparticles and nanocapsules

Simultaneous templating of polymer nanocapsules and entrapped silver nanoparticles.

Nanorattles made of hollow polymer nanocapsules with entrapped silver nanoparticles were synthesized in one step by using lipid vesicles as templates. Free radical photoinitiator facilitated both polymerization within the bilayer and formation of metal nanoparticles in the aqueous core.

Single-component Polymer Nanocapsules for Drug Delivery Application

The design of delivery vehicles for transporting anticancer drugs to tumor sites has gained traction during the past few decades. Utilizing polymer-based materials has played an important role in the development of such systems, largely because of the ability to prepare polymers with tailored properties, including biocompatibility, size, structure, and functionality. Several polymer-based vehic...