منابع مشابه
Steroidal alkaloids of Veratrum lobelianum Bernh. and Veratrum nigrum L.
Twelve steroidal alkaloids were isolated from four populations of Veratrum lobelianum Bernh. and Veratrum nigrum L. Full NMR data for veralosinine (1), and extensive 1H NMR data for veralosine (3) and teinemine (5) are presented here for the first time. (+/-)-15-O-(2-Methylbutyroyl)germine (10) is undescribed up to now. The antiproliferative activities of veranigrine, veralosinine, and neogermi...
متن کاملSteroidal alkaloids from Veratrum taliense
Phytochemical reinvestigation of the roots and rhizomes of Veratrum taliense yield three known (solanidine, veramiline-3-0-~D-glucopyranoside and stenophylline B-3-0-~D-glucopyranoside) and two novel steroidal alkaloids. The structures of the new compounds have been established by a combination of spectroscopic methods as 3angeloylzygadenine-I3-N-oxide and (20S,25S)-22,26-epiminocholesta-5,22-d...
متن کاملAlkaloids from Veratrum album subsp. lobelianum
I n our preceding paper [1] we reported t h e isolation of a novel, amorphous ester alkaloid from Veratrum album subsp. lobelianum (BERNH.) Suessenguth. This al kaloid has been found, together with protoveratrine A, germitetrine and veratroylzygadenine in the ester alkaloid fraction [2]. Acetylveratroylgermine designated originally amorphous alkaloid [1] [a]f) + 6 . 6 ° (chloroform) has, accor...
متن کاملAlkaloids from Veratrum taliense Exert Cardiovascular Toxic Effects via Cardiac Sodium Channel Subtype 1.5.
Several species of the genus Veratrum that produce steroid alkaloids are commonly used to treat pain and hypertension in China and Europe. However, Veratrum alkaloids (VAs) induce serious cardiovascular toxicity. In China, Veratrum treatment often leads to many side effects and even causes the death of patients, but the pathophysiological mechanisms under these adverse effects are not clear. He...
متن کاملA toxic self-made beverage: Analytics of alkaloids from Veratrum album by LC-MS/MS
A 49-year-old man consumed two glasses (approx. 2 x 20 ml) of a beverage containing yellow gentian (Gentiana lutea). Shortly after ingestion, he developed nausea, vomiting and oral paraesthesia. On admission to the hospital he suffered from severe bradycardia and hypotension and he was treated with activated charcoal, antiemetics, atropine and i.v. volume. The patient completely recovered from ...
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ژورنال
عنوان ژورنال: Heart
سال: 1991
ISSN: 1355-6037
DOI: 10.1136/hrt.65.5.286