Ventromedial Frontal Lobe Damage Disrupts Value Maximization in Humans
نویسندگان
چکیده
منابع مشابه
Ventromedial frontal lobe damage disrupts value maximization in humans.
Recent work in neuroeconomics has shown that regions in orbitofrontal and medial prefrontal cortex encode the subjective value of different options during choice. However, these electrophysiological and neuroimaging studies cannot demonstrate whether such signals are necessary for value-maximizing choices. Here we used a paradigm developed in experimental economics to empirically measure and qu...
متن کاملVentromedial frontal lobe damage disrupts the accuracy, but not the speed, of value-based preference judgments.
The ventromedial frontal lobe (VMF) plays a role in decision making, but its precise function remains unclear. Several lines of evidence suggest that VMF is involved in representing the economic value of options. A prior study from our lab has shown that patients with lesions to the VMF are less consistent than controls in making simple preference judgments between stimuli presented in pairs. H...
متن کاملDifferent underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans.
Ventromedial prefrontal cortex (VMF) damage can lead to impaired decision-making. This has been studied most intensively with the Iowa gambling task (IGT), a card game that asks subjects to overcome an initial attraction to high-payoff decks as losses begin to accrue. VMF subjects choose from the high risk decks more often than controls, but the fundamental impairments driving poor performance ...
متن کاملOrbitofrontal contributions to value-based decision making: evidence from humans with frontal lobe damage.
The work described here aims to isolate the component processes of decision making that rely critically on particular subregions of the human prefrontal cortex, with a particular focus on the orbitofrontal cortex. Here, experiments isolating specific aspects of decision making, using very simple preference judgment and reinforcement learning paradigms, were carried out in patients with focal fr...
متن کاملDeciding how to decide: ventromedial frontal lobe damage affects information acquisition in multi-attribute decision making.
Ventromedial frontal lobe (VMF) damage is associated with impaired decision making. Recent efforts to understand the functions of this brain region have focused on its role in tracking reward, punishment and risk. However, decision making is complex, and frontal lobe damage might be expected to affect it at other levels. This study used process-tracing techniques to explore the effect of VMF da...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2011
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.6527-10.2011