منابع مشابه
Ventricular arrhythmias in Chagas disease.
Sudden death is one of the most characteristic phenomena of Chagas disease, and approximately one-third of infected patients develop life-threatening heart disease, including malignant ventricular arrhythmias. Fibrotic lesions secondary to chronic cardiomyopathy produce arrhythmogenic substrates that lead to the appearance and maintenance of ventricular arrhythmias. The objective of this study ...
متن کاملRelationship between Fibrosis and Ventricular Arrhythmias in Chagas Heart Disease Without Ventricular Dysfunction
BACKGROUND Patients with Chagas disease and segmental wall motion abnormality (SWMA) have worse prognosis independent of left ventricular ejection fraction (LVEF). Cardiac magnetic resonance (CMR) is currently the best method to detect SWMA and to assess fibrosis. OBJECTIVE To quantify fibrosis by using late gadolinium enhancement CMR in patients with Chagas disease and preserved or minimally...
متن کاملCan chronotropic incompetence predict life-threatening ventricular arrhythmias in patients with stable ischemic heart disease?
Background: Chronotropic incompetence has prognostic value of all-cause and cardiovascular mortality in both patients with asymptomatic and symptomatic ischemic heart disease (IHD), regardless of traditional risk factors. The aim of this study was to investigate the relationship between chronotropic response during exercise test and the development of ventricular arrhythmias. Methods: 153 pati...
متن کاملNew predictors of malignant ventricular arrhythmias in Chagas disease: searching for the holy grail.
Of great frequency are also the sudden deaths in the cardiac forms of the disease. This fact constitutes one of the most curious notes in the clinical history of this trypanosomiasis, the lethality of which and number of deaths is really surprising. It being rare for families living in infested zones not to report the loss of one or more of its members in this way. Sometimes they die while stil...
متن کاملMedical treatment of cardiac arrhythmias in Chagas' heart disease.
There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1, 1,000mg/d), phenytoin (4-6mg/d), mexiletine 600-1,200mg/d), propafenone (900mg/d), amiodarone (loading: 1,000mg/d, 10-14 days; maintenance 200-600mg/d), and sotalol (320mg/d) had efficacy and tolerance ranging...
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ژورنال
عنوان ژورنال: Revista da Sociedade Brasileira de Medicina Tropical
سال: 2015
ISSN: 1678-9849,0037-8682
DOI: 10.1590/0037-8682-0003-2014