Vasorelaxant effects of Angelica decursiva root on isolated rat aortic rings
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چکیده
منابع مشابه
Vasorelaxant effects of Angelica decursiva root on isolated rat aortic rings
BACKGROUND Hypertension is one of the most important risk factors for cardiovascular disease (CVD) and a worldwide problem. Despite increases in the development of synthetic drugs for hypertension treatment, the rate of untreated and uncontrolled hypertension remains high. These drugs are effective, but can also cause side effects. Approximately 80% of the world population uses herbal medicines...
متن کاملInvestigation of the mechanisms of Angelica dahurica root extract-induced vasorelaxation in isolated rat aortic rings
BACKGROUND The root of Angelica dahurica Bentham et Hooker (Umbelliferae) has been used as a traditional medicine for colds, headache, dizziness, toothache, supraorbital pain, nasal congestion, acne, ulcer, carbuncle, and rheumatism in China, Japan, and Korea. Interestingly, it has been used in the treatment of vascular diseases including hypertension. The aim of this study was to provide pharm...
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The root of Ostericum koreanum Maximowicz has been used as a traditional medicine called "Kanghwal" in Korea (or "Qianghuo" in China). The purpose of this study was to investigate the vasorelaxant activity and mechanism of action of an ethanol extract of the O. koreanum root (EOK). We used isolated rat aortic rings to assess the effects of EOK on various vasorelaxant or vasoconstriction factors...
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متن کاملLovastatin Incubation Improves Acetylcholine-Induced Relaxation in Isolated Aortic Rings of Diabetic Rat
To evaluate the acute effect of lovastatin on diabetic endothelial dysfunction, we examined this effect on the aortic rings of streptozotocin-diabetic rats. The endothelial function was assessed in aortic rings isolated from diabetic rats, 12 weeks after treatment with streptozotocin (45 mg/kg, i.p.). The concentration-response curve to acetylcholine (Ach) in the aortic rings precontracted with...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2017
ISSN: 1472-6882
DOI: 10.1186/s12906-017-1965-z