منابع مشابه
is psoriasis an autoimmune disease?
psoriasis is a chronic, inflammatory and proliferative skin disease that has a wide distribution throughout the world. the immune system plays a critical role in developing this disease. in this survey, we have studied 50 patients suffering from psoriasis and 50 control subjects for various immunological factors, simultaneously. anti-stratum corneum (sc) antibody was evaluated by immunofluoresc...
متن کاملPsoriasis and Paget's disease.
A case is described of localized psoriasis developing in response to Paget's disease of the underlying bone.
متن کاملPsoriasis, a Systemic Disease?
It has long been recognized the epidemiological association of psoriasis, especially the most severe forms, with several diseases that share a common pathogenic substrate involving TNF-α and different target organs (arthritis and Crohn disease, for example), as well as an increased risk of coronary heart disease and occlusive cardiovascular disease. In the patient with severe psoriasis there is...
متن کاملInterleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease.
OBJECTIVE Interleukin (IL)-17A is regarded as an important cytokine to drive psoriasis, an inflammatory skin disease marked by increased cardiovascular mortality. We aimed to test the hypothesis that overproduction of IL-17A in the skin leading to dermal inflammation may systemically cause vascular dysfunction in psoriasis-like skin disease. APPROACH AND RESULTS Conditional overexpression of ...
متن کامل[Psoriasis and cardiovascular disease].
Psoriasis is a common, chronic and systemic inflammatory disease associated with several comorbidities, such as obesity, hypertension, diabetes, dyslipidaemia and metabolic syndrome, but also with an increased risk of cardiovascular disease, like myocardial infarction or stroke. The chronic inflammatory nature of psoriasis has been suggested to be a contributing and potentially independent risk...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2009
ISSN: 0022-202X
DOI: 10.1038/jid.2009.268