Vascular access considerations for extracorporeal photopheresis
نویسندگان
چکیده
منابع مشابه
[Extracorporeal photopheresis in dermatology].
Extracorporeal photochemotherapy or photopheresis is an immunomodulatory therapy that combines leukapheresis with phototherapy. Blood from the patient is processed to give a leukocyte-rich plasma, which is then treated ex vivo with a photosensitizer and ultraviolet A radiation before reinfusion back into the patient. The exact mechanism of action of photopheresis has not been fully elucidated a...
متن کاملExtracorporeal Photopheresis for Non-skin GvHD.
Graft versus host disease (GvHD) is one of the most feared adverse events of allogeneic hematopoietic stem cell transplantation. In severe grades of GvHD patients die from infections due to impairment of their immune defense or therapy-refractory involvement of intestines, liver and lung. Extracorporeal photopheresis is an effective treatment for acute and chronic graft versus host disease with...
متن کاملClinical Results of Extracorporeal Photopheresis.
Extracorporeal photopheresis (ECP) is a combination of leukapheresis and photodynamic therapy in which blood is treated with photoactivable drugs which are then activated with ultraviolet light and re-infused to the patient. It has been used successfully for more than 30 years in the treatment of erythrodermic cutaneous T-cell lymphoma (CTCL) and over 20 years for chronic graft-versus-host dise...
متن کاملExtracorporeal Photopheresis: Scientific and Technical Considerations for Improving Clinical Management of Patients
Starting at the end of 90’s, and derived from PUVA therapy, arose the concept of modulation of inappropriate immune conflicts by direct action of UVA on immunocompetent cells (lymphocytes, antigen processing cells). After the inactivation of T-cells in vitro and ex vivo, was demonstrated, the development step-by-step aimed to process large amounts of the so-called peripheral mononuclear cells. ...
متن کاملExtracorporeal photopheresis: how, when, and why.
Extracorporeal photopheresis (ECP) is a well-tolerated procedure that suppresses T-lymphocyte activity in a clonally-specific way. It is an effective therapy that has established indications in the management of cutaneous T-cell lymphoma, graft-versus-host disease and some scenarios of solid-organ transplant rejection. It is being used increasingly around the world. Its applications are evolvin...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2018
ISSN: 0041-1132
DOI: 10.1111/trf.14500