منابع مشابه
Key issues in varicella-zoster virus latency.
The molecular mechanisms by which varicella-zoster virus (VZV) causes a latent infection in human trigeminal and spinal ganglia are not well understood. It is known that VZV establishes latency in ganglia following the primary infection causing varicella (chickenpox), and that the virus may reactivate after years of dormancy to produce herpes zoster (shingles). Two key issues have been the cell...
متن کاملLatency of varicella zoster virus; a persistently perplexing state.
Varicella zoster virus (VZV) is the herpesvirus which causes the childhood disease varicella, also known as chickenpox, and the adult disease herpes zoster, also known as shingles. These distinct diseases are separated by a lengthy period of latency, often lasting decades, in which the virus resides within the ganglia of the host. VZV latency and reactivation from it have, for the most part, be...
متن کاملVaricella zoster virus.
Because of its ability to produce two clinically distinct disease entities (chickenpox and shingles), varicella zoster virus (VZV) is an unusual etiologic agent. Although in the past viral exanthems were mostly only of academic interest to the practitioner, the development of antiviral agents and the newly approved varicella (OKA) vaccine have increased the clinical significance. Also, with the...
متن کاملVaricella-zoster virus myeloencephalitis☆
A 47-year-old woman with history of systemic lupus erythematous on prednisolone presented to our emergency department with fever and back pain for 5 days along with progressive muscle weakness on left lower leg. Cerebrospinal fluid (CSF) revealed pleocytosis with mononuclear leukocyte predominance. Brain and spine Magnetic Resonance Imaging (MRI) revealed multiple high intensity areas on cerebr...
متن کاملVaricella-Zoster Virus
Varicella-zoster virus (VZV) is one of the eight herpesviruses that infects humans. The virus causes two diseases, varicella (chickenpox) and zoster (shingles) (1). Varicella is primarily an illness of children, although as many as 5% of adults in the United States may be susceptible. Zoster is caused by reactivation of latent VZV infection in sensory ganglia, which resulted during the attack o...
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ژورنال
عنوان ژورنال: Future Virology
سال: 2011
ISSN: 1746-0794,1746-0808
DOI: 10.2217/fvl.10.90