Vancomycin Therapeutic Drug Monitoring in Term Newborn Infants 1457
نویسندگان
چکیده
منابع مشابه
Therapeutic drug monitoring of vancomycin.
Vancomycin, a glycopeptide antibiotic, was developed-and released in the 1950's for the treatment of aerobic gram-positive infections and has been widely used mainly in the treatment of methicillin-resistant Staphylococcus aureus infections. Early reports regarding the possibility of nephrotoxicity and ototoxicity led to concern about the use of vancomycin and the need to monitor serum concentr...
متن کاملTherapeutic drug monitoring of amikacin in preterm and term infants.
INTRODUCTION Amikacin is a commonly-prescribed drug used for the empirical treatment of bacterial infections in neonates. A marked change in the pharmacokinetics of amikacin has been reported during neonatal life. Amikacin has a very narrow therapeutic range and can cause very serious side effects such as nephrotoxicity and ototoxicity. The current therapeutic dose of amikacin, i.e. 15 mg/kg of...
متن کاملMonitoring the treatment of sepsis with vancomycin in term newborn infants.
UNLABELLED A prospective study was conducted to determine if standardized vancomycin doses could produce adequate serum concentrations in 25 term newborn infants with sepsis. PURPOSE The therapeutic response of neonatal sepsis by Staphylococcus sp. treated with vancomycin was evaluated through serum concentrations of vancomycin, serum bactericidal titers (SBT), and minimum inhibitory concentr...
متن کاملA review of vancomycin therapeutic drug monitoring recommendations in Scotland.
NephSAP 2007; 6: 199–280. 6. Halperin ML, Kamel KS. Potassium. Lancet 1998; 352: 135–40. 7. Grimm PR, Sansom SC. BK channels in the kidney. Curr Opin Nephrol Hypertens 2007; 16: 430–6. 8. Oster JR, Singer I, Thatte L et al. The polyuria of solute diuresis. Arch Intern Med 1997; 157: 721–9. 9. Mittal VK, Pierce AK, Priestley JC. Use of probenecid in ticarcillin-induced hypokalemia. Clin Ther 198...
متن کاملClinical efficacy of therapeutic drug monitoring in patients receiving vancomycin.
Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did not (non-TDM group, n=111). Creatinine clearance (CLcr) values decreased significantly after the ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-01478