Vanadyl sulfate prevents fructose-induced hyperinsulinemia and hypertension in rats.

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Vanadyl sulfate prevents fructose-induced hyperinsulinemia and hypertension in rats.

To determine whether insulin resistance and hyperinsulinemia are causally related to fructose-induced hypertension, we used vanadyl sulfate, a drug that improves insulin sensitivity in rats. Chronic oral vanadyl treatment was initiated in 6-week-old male Sprague-Dawley rats. One week after vanadyl was started, rats were fed either normal rat chow or a fructose-enriched diet. Plasma glucose and ...

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Effect of Vanadyl Sulfate on Fructose-Induced Insulin Resistance Rat

Insulin resistance syndrome, also referred to as the metabolic syndrome or syndrome X, refers to a constellation of common metabolic and cardiovascular disorders (e.g. obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia), which are all cardiovascular risk factors. Insulin resistance can be induced by fructose-rich diet in rats. We investigated the effect of vanadyl sulfate (0.2 mg...

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Renal denervation prevents and reverses hyperinsulinemia-induced hypertension in rats.

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Effect of Vanadyl Sulfate on Fructose-Induced Insulin Resistance Rat

Insulin resistance syndrome, also referred to as the metabolic syndrome or syndrome X, refers to a constellation of common metabolic and cardiovascular disorders (e.g. obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia), which are all cardiovascular risk factors. Insulin resistance can be induced by fructose-rich diet in rats. We investigated the effect of vanadyl sulfate (0.2 mg...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1994

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.23.3.308