Validated LC Method for the Estimation of Dorzolamide HCl (Carbonic Anhydrase Inhibitor) in Ophthalmic Solutions
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چکیده
منابع مشابه
2135 Systemic pharmacokinetics and carbonic anhydrase inhibition of dorzolamide
fir-pose: Dorzolamide @ORE) is a topical carbonic anhydrase (CA) inhibitor that is approved for treatment of open-angle glauccma and ocular hypertension. DORE exerts its effects directly in the eye at substantially lower doses and therefore with less systemic exposure than oral CA inhibitors To evaluate DORZ's potential for systemic CA inhibition, maximum systemic exposure was simulated through...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2012
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2012/258261