Valganciclovir-induced lecuopenia in renal transplant recipients treated with mycophenolate mofetil
نویسندگان
چکیده
منابع مشابه
BENEFICIAL EFFECT OF LOW DOSE CYCLOSPORINE WITH MMF (MYCOPHENOLATE MOFETIL) IN RENAL ALLOGRAFT RECIPIENTS
Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studi...
متن کاملThe use of mycophenolate mofetil in liver transplant recipients.
Mycophenolate mofetil is an important drug in the modern immunosuppressive arsenal. Mycophenolate mofetil is the semisynthetic morpholinoethyl ester of mycophenolate acid. Mycophenolate acid prevents T and B cell proliferation by specifically inhibiting a purine pathway required for lymphocyte division. This paper extensively reviews the experience of mycophenolate mofetil use in liver transpla...
متن کاملUnexpected rate of severe leucopenia with the association of mycophenolate mofetil and valganciclovir in kidney transplant recipients.
Here, we report on a patient with a gram-negative CAPDrelated peritonitis presumably caused by an ascending infection due to fallopian tube capture of the CAPD catheter. An 81-year-old woman with coronary heart disease and end-stage renal disease as a consequence of diabetes mellitus underwent an uncomplicated surgical insertion of a Tenckhoff catheter. After 2 weeks, CAPD was started without d...
متن کاملComparing outcomes associated with dose manipulations of enteric-coated mycophenolate sodium versus mycophenolate mofetil in renal transplant recipients.
BACKGROUND This study assessed the incidence of reported gastrointestinal (GI) complications in patients treated with enteric-coated mycophenolate sodium (EC-MPS) versus mycophenolate mofetil (MMF) and to examine the impact of dose manipulations on biopsy-proven acute rejection (BPAR). METHODS A retrospective study was conducted in 379 renal transplant recipients initiated on EC-MPS or MMF th...
متن کاملLeukopenia in kidney transplant patients with the association of valganciclovir and mycophenolate mofetil.
Cytomegalovirus (CMV) is the most common viral infection after transplantation. Valganciclovir (VGC) is established for prophylaxis and treatment of CMV infections, but leukopenia which appears in 10% to 13% (severe in 4.9%) is the principal side effect. We have recently noted an increased incidence of leukopenia and severe neutropenia among our renal transplant patients and thought to identify...
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ژورنال
عنوان ژورنال: International Journal of Surgery
سال: 2014
ISSN: 1743-9191
DOI: 10.1016/j.ijsu.2014.08.181