منابع مشابه
Vagal nerve stimulation in heart failure.
It has been estimated that the prevalence of heart failure with a reduced ejection fraction exceeds 20 million patients worldwide— about 2% of the general population in the Western world—and that the annual incidence is . 2 million patients per year. The mortality of heart failure exceeds that of many malignancies. Significant healthcare improvements have been made with regard to pharmaceutical...
متن کاملVagal nerve stimulation in chronic heart failure: an antiinflammatory intervention?
Failure: An Antiinflammatory Intervention? To the Editor: Li et al1 recently reported that vagal nerve stimulation improved survival in otherwise untreated rats with heart failure secondary to left coronary artery ligation. Although this finding is indeed intriguing and of potential therapeutic importance, the authors are understandably speculative about the possible mechanisms underlying this ...
متن کاملHeart period variability during vagal nerve stimulation
Vagal nerve stimulation is an emerging therapy for epilepsy, yet little is known regarding the effects of this stimulation on heart period variability. We selected 10 patients (two female, eight male) who were receiving high-frequency, high-intensity left vagal nerve stimulation for intractable epilepsy. Electrocardiogram data were recorded for a 7 min baseline, 2.5 min of stimulation and a 7 m...
متن کاملChronic vagal nerve stimulation improves baroreflex neural arc function in heart failure rats.
We tested whether 6-wk vagal stimulation (VS) treatment improved open-loop baroreflex function in rats after myocardial infarction (MI). The following three groups of Sprague-Dawley rats were examined: normal control (NC, n = 9), MI with no treatment (MI-NT, n = 8), and MI treated with VS (MI-VS, n = 7). Under anesthesia, a stepwise input ranging from 60 to 180 mmHg was imposed on isolated caro...
متن کاملShort-term vagal nerve stimulation improves left ventricular function following chronic heart failure in rats
Increasing numbers of animal and clinical investigations have demonstrated the effectiveness of long-term electrical vagal nerve stimulation (VNS) on chronic heart failure (CHF). The present study investigated the effects of short-term VNS on the hemodynamics of cardiac remodeling and cardiac excitation-contraction coupling (ECP) in an animal model of CHF following a large myocardial infarction...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2014
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehu363