Vaccination of pigs against pseudorabies virus with plasmid DNA encoding glycoprotein D
نویسندگان
چکیده
منابع مشابه
Protective effects of intranasal vaccination with plasmid encoding pseudorabies virus glycoprotein B in mice.
Intranasal administration of plasmid DNA encoding glycoprotein B of pseudorabies virus into mice induced both serum and secretory antibody responses. These mice resisted intranasal challenge with lethal dose of the virus, but did not intraperitoneal challenge. On the other hand, intramuscular injection of the plasmid induced less secretory and higher serum antibody responses than those of intra...
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To evaluate the feasibility of using pseudorabies virus (PrV) glycoprotein B (gB) as a carrier of foot and mouth disease virus (FMDV) antigens in DNA immunization, FMDV B- and T-cell epitopes were inserted either between the two B-cell epitopes of the N-term subunit of PrV-gB (BT-PrV-gB-N-term construct) or within the B-cell epitope of the C-term subunit of PrV-gB (BT-PrV-gB-C-term construct). ...
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ژورنال
عنوان ژورنال: Vaccine
سال: 1999
ISSN: 0264-410X
DOI: 10.1016/s0264-410x(98)00349-1