Utility of topical timolol in the management of chronic non-healing foot ulcers

Background: Chronic foot ulcers often do not respond to conventional therapy and result in amputations. Treatment is protracted, expensive affects the quality of life patient. The objective study efficacy topical timolol treatment chronic non-healing feasibility its use a rural/semi-urban population. Methods: An observational, cross-sectional was conducted at tertiary hospital situated on outskirts Bengaluru from January 2021 July 2022. Sample size 95. Topical maleate solution applied day 1, 3 7 followed up days 15 30. During each visit wound assessed area ulcer measured. Repeated measures ANOVA compare 30 mean percentage reduction calculated different time intervals using post-hoc Bonferroni. Results: Demographic data: predominantly male (61.1%), age 48.74±14.8 years, lower socioeconomic background. 45.3% were diabetics. Efficacy timolol: 70.95, 51.8 39.95 cm2 respectively (p=0.001). There significant No adverse effects due observed. Conclusions: safe, inexpensive effective. Its would be beneficial country like India which has large rural