Uteroferrin Induces Lipid Peroxidation in Endometrial and Conceptus Microsomal Membranes and is Inhibited by Apotransferrin, Retinol Binding Protein, and the Uteroferrin-Associated Proteins1
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چکیده
منابع مشابه
Uteroferrin induces lipid peroxidation in endometrial and conceptus microsomal membranes and is inhibited by apotransferrin, retinol binding protein, and the uteroferrin-associated proteins.
Iron-containing proteins catalyze lipid peroxidation when combined with either H2O2 or ascorbic acid (ASC). Microsomal membranes were prepared from Day 13 endometrial and conceptus tissues (5 pigs) and from Day 30 endometrial, placental, fetal liver, and fetus minus fetal liver tissues (5 pigs). Microsomal membranes were subjected to the following in vitro treatments: 1) no treatment, 2) 50 mic...
متن کاملAssociation between uteroferrin, retinol-binding protein, and transferrin within the uterine and conceptus compartments during pregnancy in swine.
The association between uteroferrin (UF, measured as acid phosphatase [AP] activity), retinol-binding protein (RBP), and transferrin (TF), within the intrauterine environment during the estrous cycle and pregnancy was examined. Pregnant gilts were killed on Days 7, 10, 13, 16, 19, 25, 30, 40, 50, 60, 70, 80, and 90. Cyclic gilts were killed on Days 7, 10, 13, and 16. On Days 7 through 19, each ...
متن کاملThe effect of estrone and estradiol treatment on endometrial total protein, uteroferrin, and retinol-binding protein secretion during midpregnancy or midpseudopregnancy in swine.
It has been hypothesized that conceptus estrogens influence endometrial protein secretion during pregnancy in swine. To test this hypothesis, the effect of estrone and estradiol treatment from d 30 to 60 of pregnancy or pseudopregnancy on endometrial protein secretion was investigated. Pregnant (P; n = 16) and pseudopregnant (PP) gilts (n = 18) received either sham treatment or estrone or estra...
متن کاملRole of uteroferrin in placental iron transport in swine: relationship between uteroferrin levels and iron deposition in the conceptus during gestation.
This study was to examine the relationship between uteroferrin and Fe, and Fe and Cu in the fetal pig. In Exp. 1, conceptus tissues and fluids were obtained on d 30, 45, 60, 75 and 90 of gestation for Fe and Cu analyses. In fetus minus liver, total Fe and Cu increased constantly between d 30 and 90, but Fe and Cu concentrations (microgram/g dry tissue) both decreased between d 30 and 45 and the...
متن کاملConceptus, progesterone, and breed effects on uterine protein secretion in swine.
This experiment consisted of the following treatment-breed groups: 1) White crossbred gilts, 2) White crossbred gilts treated with progesterone (200 mg/d in corn oil given on d 2 and 3 after estrus), and 3) Chinese Meishan gilts. Pregnant and nonpregnant gilts (n=3 to 6) from each treatment-breed combination were assigned to be slaughtered on d 10, 11, 12, 13, and 15. At slaughter each uterine ...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1995
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod53.6.1436