Uterine cellular leiomyomata with chromosome 1p deletions represent a distinct entity
نویسندگان
چکیده
منابع مشابه
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis
Chromosomal instability is a major pathway of sporadic colon carcinogenesis. Chromosome arm 1p appears to be one of the "hot spots" in the non-neoplastic mucosa that, when deleted, is associated with the initiation of carcinogenesis. Chromosome arm 1p contains genes associated with DNA repair, spindle checkpoint function, apoptosis, multiple microRNAs, the Wnt signaling pathway, tumor suppressi...
متن کاملChromosome 1p and 19q deletions in glioblastoma multiforme.
CONTEXT Deletions on chromosomes 1p and 19q have been shown to correlate with prognosis and chemosensitivity in anaplastic oligodendrogliomas. In glioblastoma multiforme (GBM), the impact on prognosis of these alterations in GBM is unclear. OBJECTIVE The purpose of this study was to identify patients with GBM who had evidence of 1p or 19q deletions by fluorescence in situ hybridization, and c...
متن کاملGiant uterine leiomyomata.
OBJECTIVE To present the case of a patient with giant uterine leiomyomata and review literature pertinent to the subject. DESIGN Case report and literature review. SETTING A major university, tertiary-care hospital. PATIENT(S) One patient, with said pathology, who gave informed consent for exploratory laparotomy, total abdominal hysterectomy, and bilateral salpingo-ophorectomy. INTERVEN...
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In this report two non consanguineous children are presented with strikingly similar phenotypes confirming the existence of a characteristic phenotype due to a ring chromosome 14 formation.
متن کاملDistinct Deletions of Chromosome 9p Associated with Melanoma
Deletions of DNA on chromosome 9p21-22 are frequently observed in cells derived from melanomas, gliomas, non-small cell lung cancers, and acute lymphoblastic leukemia. The minimal deletion shared by the latter three cancers extends from the interferon-a locus towards the centromere; its centromeric end is flanked by the gene encoding methylthioadenosine phosphorylase. We have determined that th...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2014
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2014.01.011