Uterine abnormalities and embryo implantation: clinical opinion altered by peer debate
نویسندگان
چکیده
منابع مشابه
Uterine Receptivity to Embryo Implantation
It is both flattering and humbling to be asked to address this topic, since quite a few people at this meeting could address it equally well or better. In fact, Koji wrote a review with almost exactly the same title 20 years ago (1). However, each of us would address the area somewhat differently. Over the years I have had the privilege of examining blastocysts and implantation sites of a large...
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Implantation of the fertilized egg into the maternal uterus depends on the fine balance between inflammatory and anti-inflammatory processes. Whilst regulatory T cells (Tregs) are reportedly involved in protection of allogeneic fetuses against rejection by the maternal immune system, their role for pregnancy to establish, e.g., blastocyst implantation, is not clear. By using 2-photon imaging we...
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Implantation is a complex developmental process that involves an intimate “crosstalk” between the embryo and uterus. Synchronized development of the embryo to the blastocyst stage and differentiation of the uterus to the receptive state are essential to this process. Successful execution of the events of implantation involves participation of steroid hormones, locally derived growth factors, cy...
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Implantation of the fertilized egg into the maternal uterus is a crucial step in pregnancy establishment. Increasing evidence suggests that its success depends on various cell types of the innate immune system and on the fine balance between inflammatory and anti-inflammatory processes. In addition, it has recently been established that regulatory T cells play a superordinate role in dictating ...
متن کاملDysregulated cannabinoid signaling disrupts uterine receptivity for embryo implantation.
The mechanisms by which synchronized embryonic development to the blastocyst stage, preparation of the uterus for the receptive state, and reciprocal embryo-uterine interactions for implantation are coordinated are still unclear. We show in this study that preimplantation embryo development became asynchronous in mice that are deficient in brain-type (CB1) and/or spleen-type (CB2) cannabinoid r...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2007
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(10)61045-0