Using whole immune system characterization (immune profiling) to identify immune biomarkers to determine patient selection, dosing, and efficacy of new immune therapies
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چکیده
منابع مشابه
Using whole immune system characterization (immune profiling) to identify immune biomarkers to determine patient selection, dosing, and efficacy of new immune therapies
Methods We have developed a systems based approach to understand immunosuppression in cancer patients by combining comprehensive whole blood quantitative flow cytometry and classical bioinformatics analyses. Our first generation immune profile analysis identified a unique biomarker consisting of the ratio of CD4+ T cells to CD14HLA-DR monocytes that correlate with survival rates in over 90 pati...
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ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2015
ISSN: 2051-1426
DOI: 10.1186/2051-1426-3-s2-p90