Using trajectory analyses to refine phenotype for genetic association: conduct problems and the serotonin transporter (5HTTLPR)
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چکیده
منابع مشابه
Association between the serotonin transporter polymorphism (5HTTLPR) and subjective happiness level in Japanese adults
Background: An epidemiological study in the USA recently reported that variations in the serotonin transporter gene-linked polymorphic region (5HTTLPR) can influence subjective well-being or happiness; specifically, individuals with long polymorphisms (L-allele carriers), associated with increased serotonin reuptake activity, reported significantly higher levels of life satisfaction compared to...
متن کاملAssociation between intelligence quotient and the 5HTTLPR polymorphism of human serotonin transporter coding gene
Association between common intelligence quotient (IQ) and S and L alleles of functional 5HTTLPR polymorphism causing respectively low and high expression of human serotonin transporter coding gene was studied in young (19-35 years, 50 men and 76 women) and older (>55 years, 39 men and 43 women) Caucasian subjects. They were students, scientists, technicians and administrative staff of Novosibir...
متن کاملGenetic association of the serotonin transporter in pulmonary arterial hypertension Running Head: Serotonin transporter in PAH
word count: 159
متن کاملGenetic association of the serotonin transporter in pulmonary arterial hypertension.
RATIONALE The bone morphogenetic receptor type II gene is the major genetic determinant for the inherited form of pulmonary arterial hypertension. However, deleterious mutations of this gene are not observed in the majority of subjects who develop the condition spontaneously and familial disease displays age- and sex-dependent penetrance, indicating the requirement for additional environmental ...
متن کاملSerotonin Transporter Genotype (5HTTLPR) Moderates the Longitudinal Impact of Atypical Attachment on Externalizing Behavior.
OBJECTIVE To test whether genotype of the serotonin transporter-linked polymorphic region (5HTTLPR) and atypical attachment interact to predict externalizing psychopathology prospectively in a sample of children with a history of early institutional care. METHODS Caregiver report of externalizing behavior at 54 months was examined in 105 children initially reared in institutional care and enr...
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ژورنال
عنوان ژورنال: Psychiatric Genetics
سال: 2010
ISSN: 0955-8829
DOI: 10.1097/ypg.0b013e32833a20f1