Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
نویسندگان
چکیده
منابع مشابه
How do mutations cause disease?
The identification to date of most of the mutations responsible for monogenic disorders with familial inheritance has opened schematically two broad fields for cardiovascular research in the next decade or two: that of how a given mutation with a strong deleterious effect cause a disease, and that of how a number of genes, each with a weak implication in the disease phenotype, combine their eff...
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1 Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK 2 Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK 3 IfADo – Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany 4 Friedrich-Baur Institute, Ludwig Maximilian University, Munich, Germany ...
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ژورنال
عنوان ژورنال: CourseSource
سال: 2016
ISSN: 2332-6530
DOI: 10.24918/cs.2016.16