Use of the EMPOWER brochure to deprescribe sedative-hypnotic drugs in older adults with mild cognitive impairment

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Use of the EMPOWER brochure to deprescribe sedative-hypnotic drugs in older adults with mild cognitive impairment

BACKGROUND Evidence-based mailed educational brochures about the harms of sedative-hypnotic use lead to discontinuation of chronic benzodiazepine use in older adults. It remains unknown whether patients with mild cognitive impairment (MCI) are able to understand the information in the EMPOWER brochures, and whether they achieve similar rates of benzodiazepine discontinuation. METHODS Post-hoc...

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Prevalence of Cognitive Impairment in Community-Dwelling Older Adults

Introduction: Mild cognitive impairment can be considered as an intermediate clinical state between normal cognitive aging and mild dementia. Elderly people with this impairment represent an at-risk group for the development of dementia. The aim of this study was to investigate the prevalence of cognitive impairment in community-dwelling older adults by Mini-Mental State Examination (MMSE) and ...

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Separation of Sedative – Hypnotic Drugs with Mixed Micellar Liquid Chromatography

Separation of ten sedative- hypnotic drugs was performed by RP-HPLC using mixed micellar mobile phase. Effect of temperature, type and amount of organic modifier in mobile phase on efficiency (N) and asymmetry factor (B/A) showed that, the appropriate conditions for a good separation were 35°C and 7% (V/V) butanol in mobile phase.  Variations of selectivity factor versus butanol concent...

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Sedative-Hypnotic and Anxiolytic Drugs

The primary use of sedative–hypnotic and anxiolytic drugs is to encourage calmness (anxiolytics or sedatives) or to produce sleep (sedative–hypnotics). All people are subject to states of emotional tension and uneasiness. For otherwise healthy individuals, these occasions are usually sufficiently mild and short that pharmacological intervention is unnecessary. However, at times the symptoms of ...

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Management of insomnia and long-term use of sedative-hypnotic drugs in older patients.

hypnotic drugs are prescribed to many older adults despite the nearly 5-fold increased risk of adverse cognitive events associated with their use (95% confidence interval [CI] 1.47 to 15.47), the 2.6-fold increased risk of adverse psychomotor events (95% CI 1.12 to 6.09), the association with falls and hip fractures and the 5-fold increased risk of hospital admission after a motor vehicle colli...

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ژورنال

عنوان ژورنال: BMC Geriatrics

سال: 2017

ISSN: 1471-2318

DOI: 10.1186/s12877-017-0432-5