Use of contrast sensitivity measurement in the detection of subclinical ethambutol toxic optic neuropathy.

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Use of contrast sensitivity measurement in the detection of subclinical ethambutol toxic optic neuropathy.

Contrast sensitivity was measured by means of Arden grating plates in 100 patients on medication for pulmonary tuberculosis. The scores were abnormal in 38.2% of the patients whose therapy included ethambutol for three months, and 36.7% of the patients on similar treatment for six months. In comparison with age matched groups of patients on a regimen where streptomycin replaced ethambutol a sta...

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Ethambutol-associated optic neuropathy.

INTRODUCTION Ethambutol is used in the treatment of tuberculosis, which is still prevalent in Southeast Asia, and can be associated with permanent visual loss. We report 3 cases which presented with bitemporal hemianopia. CLINICAL PICTURE Three patients with ethambutol-associated toxic optic neuropathy are described. All 3 patients had loss of central visual acuity, colour vision (Ishihara) a...

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The rare ethambutol-induced optic neuropathy

RATIONALE Ethambutol-induced optic neuropathy (EON) is a well-known complication that results from the use of ethambutol. The ocular manifestations of EON include painless loss of central vision and cecocentral scotomas in the visual field. PATIENT CONCERNS A 75-year-old Chinese Han man suffered from this rare ocular disorder because he took ethambutol for about 8 months. DIAGNOSES He was d...

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Bilateral anterior toxic optic neuropathy and the use of infliximab.

Three cases of bilateral optic neuropathy were reported recently to the Netherlands Pharmacovigilance Centre Lareb. Patient 1, a 54 year old man, had blurred vision 34 days after he was given a third dose of infliximab for rheumatoid arthritis. He was also taking leflunomide, prednisone, naproxen, diazepam, fluoxetine, famotidine, and metoprolol, and acetaminophen or codeine. He had 20/30 visio...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1987

ISSN: 0007-1161

DOI: 10.1136/bjo.71.3.192