Urotensin-II System in Genetic Control of Blood Pressure and Renal Function
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چکیده
منابع مشابه
Urotensin-II System in Genetic Control of Blood Pressure and Renal Function
Urotensin-II controls ion/water homeostasis in fish and vascular tone in rodents. We hypothesised that common genetic variants in urotensin-II pathway genes are associated with human blood pressure or renal function. We performed family-based analysis of association between blood pressure, glomerular filtration and genes of the urotensin-II pathway (urotensin-II, urotensin-II related peptide, u...
متن کاملRenal Urotensin II System Plays Roles in the Regulation of Blood Pressure in Dahl Salt-Resistant Rat
Introduction. Dahl salt-resistant (SR) animal models are similar to peritoneal dialysis patients with fluid volumes overload with normal blood pressure in hemodynamic profiles. We will verify the roles of UII in the regulation of blood pressure in these animal models. Methodology. The Dahl salt-sensitive (SS) and SR rats and UII receptor gene knocked out (KO) mice were placed on a high-salt die...
متن کاملGenetic control of blood pressure in mice.
HE role of genetics in determining arterial blood pressure has been the s u b of numerous papers in the medical literature. Familial aggregation of blood pressure levels is well documented in human populations (summarized by MCKUSICK 1960; SCHTNEITZER et al. 1962; ROBERTS 1964). Although there is little doubt that genetic factors to some degree determine systolic blood pressure levels. there is...
متن کاملThe urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats.
Urotensin-II (U-II) is a cyclic peptide that acts through a specific G-protein-coupled receptor, UT receptor. Urotensin-II and UT receptors have been described in pancreas and kidney, but their function is not well understood. We studied the effects of chronic treatment of diabetic rats with the orally active selective U-II receptor antagonist palosuran. Streptozotocin treatment causes pancreat...
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translation as a comunicative process is always said to be associated with various aspects of meaning loss or gain. subtitling as a mode of translating, due to special discoursal and textual conditions imposed upon it, is believed to be an obvious case of this loss or gain. presenting the spoken sound track of a film in writing and synchronizing the perception of this text by the viewers with...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0083137