Urine Albumin-to-Creatinine Ratio: What's in a Number?

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Urine albumin-to-creatinine ratio: what's in a number?

1. Liu Y: New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 21: 212–222, 2010 2. Zeisberg M, Neilson EG: Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 119: 1429–1437, 2009 3. Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R: TGFbeta receptor deletion in the renal collecting system exacerbates fibrosis. J Am S...

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Urine albumin to creatinine ratio-response to exercise in diabetes.

Albuminuria was studied in 40 diabetic children before and after a standardised exercise test, and also in 21 normal children; the results are expressed as geometric mean (95% range) of urine albumin:urine creatinine ratio (mg/mg). There was no significant difference between the mean resting albumin:creatinine ratio in the two groups, or between these ratios before and after exercise in the nor...

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Influence of urine creatinine on the relationship between the albumin-to-creatinine ratio and cardiovascular events.

BACKGROUND AND OBJECTIVES In the albumin-to-creatinine ratio (spot-ACR), urine creatinine corrects for tonicity but also reflects muscle mass. Low muscle mass is associated with cardiovascular disease (CVD). We hypothesized that the spot-ACR would be higher in women, lower-weight persons, and older individuals, independent of timed urine albumin excretion (24hr-UAE), and accordingly, that spot-...

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Urine albumin to creatinine ratio - response to exercise in diabetes 309

2 Deckert T, Poulsen JE, Larsen M. Prognosis of diabetics with diabetes onset before the age of thirty-one: I: survival, causes of death and complications. Diabetologia 1978:14:363-70. 3 Mogcnsen CE. Early functional and morphologic vascular renal consequences of the diabetic state. Diabetologia 1979;17:71-6. 4 Steno Study Group. Effect of 6 months of strict metabolic control on eye and kidney ...

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An effective indicator in predicting cardiovascular events: urine albumin to creatinine ratio.

OBJECTIVE To study elderly hypertensive patients with trace albuminuria (urine albumin to creatinine ratio (UACR)) and the relationship between the occurrence of new cardiovascular events, to provide a basis for early prevention in elderly patients with high blood pressure. PATIENTS AND METHODS A total of 3564 elderly patients with high blood pressure were enrolled in the study. Based on UACR...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2010

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.2010060614