URINARY LOW MOLECULAR PROMOTER OF CALCIUM OXALATE MONOHYDRATE CRYSTAL AGGREGATION
نویسندگان
چکیده
منابع مشابه
[Effect of urinary material and glycosaminoglycans on calcium oxalate monohydrate crystal aggregation].
We have examined by the coulter counter method whether some substances promote or inhibit calcium oxalate monohydrate crystal aggregation. The substances tested were hyaluronic acid, chondroitin sulfate and urinary lyophilized material of less than 10 k dalton fractions having aggregate activity. As a result, hyaluronic acid promoted aggregation at low concentrations but inhibited it at higher ...
متن کاملUrinary calcium oxalate crystal growth inhibitors.
Calcium stones occur because renal tubular fluid and urine are supersaturated with respect to calcium oxalate and phosphate. The process of stone formation includes crystal nucleation, growth, aggregation, and attachment to renal epithelia. Urine contains macromolecules that modify these processes and may protect against stone formation. Attention has focused especially on inhibitors of crystal...
متن کاملReinjury risk of nano-calcium oxalate monohydrate and calcium oxalate dihydrate crystals on injured renal epithelial cells: aggravation of crystal adhesion and aggregation
BACKGROUND Renal epithelial cell injury facilitates crystal adhesion to cell surface and serves as a key step in renal stone formation. However, the effects of cell injury on the adhesion of nano-calcium oxalate crystals and the nano-crystal-induced reinjury risk of injured cells remain unclear. METHODS African green monkey renal epithelial (Vero) cells were injured with H2O2 to establish a c...
متن کاملDefining and Systematic Analyses of Aggregation Indices to Evaluate Degree of Calcium Oxalate Crystal Aggregation
Crystal aggregation is one of the most crucial steps in kidney stone pathogenesis. However, previous studies of crystal aggregation were rarely done and quantitative analysis of aggregation degree was handicapped by a lack of the standard measurement. We thus performed an in vitro assay to generate aggregation of calcium oxalate monohydrate (COM) crystals with various concentrations (25-800 μg/...
متن کاملIncreased calcium oxalate monohydrate crystal binding to injured renal tubular epithelial cells in culture.
The retention of crystals in the kidney is considered to be a crucial step in the development of a renal stone. This study demonstrates the time-dependent alterations in the extent of calcium oxalate (CaOx) monohydrate (COM) crystal binding to Madin-Darby canine kidney (MDCK) cells during their growth to confluence and during the healing of wounds made in confluent monolayers. As determined by ...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1987
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol1928.78.7_1149