Ureolytic Biomineralization Reduces Proteus mirabilis Biofilm Susceptibility to Ciprofloxacin
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چکیده
منابع مشابه
Reduced Susceptibility of Proteus mirabilis to triclosan.
Clinical isolates of Proteus mirabilis causing catheter encrustation and blockage are susceptible to the biocide triclosan (MICs of 0.2 mg/liter). Studies with laboratory models of the bladder have demonstrated that the inflation of catheter retention balloons with triclosan solutions rather than water results in the diffusion of triclosan from the balloons into the surrounding urine and the in...
متن کاملThe Ciprofloxacin Impact on Biofilm Formation by Proteus Mirabilis and P. Vulgaris Strains
BACKGROUND Proteus spp. bacilli belong to opportunistic human pathogens, which are primarily responsible for urinary tract and wound infections. An important virulence factor is their ability to form biofilms that greatly reduce the effectiveness of antibiotics in the site of infection. OBJECTIVES The aim of this study was to determine the value of the minimum concentration of ciprofloxacin t...
متن کاملAnalysis of ciprofloxacin and gentamicin diffusion in Proteus mirabilis O18 biofilm by laser interferometry method.
Laser interferometry is a measurement technique used in physical sciences, with a potential for new applications in microbiology. Our previously studies, focused on the quantitative analysis of antibiotics diffusion through membranes or their releasing from gel structure, indicate that this method might be useful in analysis of substances diffusion across the bacterial biofilms. As antibiotic -...
متن کاملThe Assessment of Proteus mirabilis Susceptibility to Ceftazidime and Ciprofloxacin and the Impact of These Antibiotics at Subinhibitory Concentrations on Proteus mirabilis Biofilms
Rods of the Proteus genus are commonly isolated from patients, especially from the urinary tracts of the catheterised patients. The infections associated with biomaterials are crucial therapeutic obstacles, due to the bactericidal resistance of the biofilm. The aim of this study was to assess the susceptibility of P. mirabilis planktonic forms to ciprofloxacin and ceftazidime, the ability to fo...
متن کاملthe ciprofloxacin impact on biofilm formation by proteus mirabilis and p. vulgaris strains
conclusions minimum biofilm eradication values of ciprofloxacin obtained in the study are close to the values of the minimal inhibition concentration (mic). results all tested strains formed a biofilm. a value of 1.0 μg/ml ciprofloxacin is mbe50 for the strains of both tested species. an mbe90 value of ciprofloxacin for isolates of p. vulgaris was 2 μg/ml and for p. mirabilis was 512 μg/ml. mat...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2016
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00203-16