Updates in Basic Research on Molecular Genetic Background of Pulmonary Hypertension
نویسندگان
چکیده
منابع مشابه
Evaluation of Pulmonary Hypertension In First Degree Relatives Of Patients With Primary Pulmonary Hypertension
Background: Pulmonary hypertension (PH) was defined for the first time in 1951 as primary pulmonary hypertension (PPH). Some studies emphasized on the role of genetics in the development of pulmonary hypertension in family members of affected patients. So, in this study we evaluated the prevalence of pulmonary hypertension in first degree family of patients with documented PPH. Methods: In thi...
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The purpose of this investigation was to assess the effect of captopril on both systemic (P.a) and pulmonary arterial pressures (PPA) in patients with high-altitude pulmonary hypertension (HAPH). Seventeen patients (mean age 44±6.8 years) with HAPH and mild to moderate systemic arterial hypertension were included in the study. All patients underwent right heart catheterization with measurem...
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PAH is caused by the obstruction of pulmonary arteries due to excessive proliferation of cells in tunica intima, tunica media and tunica adventitia along with deposition of components of extracellular matrix. The formation of occlusive lesion initiates in the tunica media, called as medial thickening, as the pulmonary arterial smooth muscle cells (PASMCs) start to proliferate. Medial thickening...
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The simple reason is that the field moves at a rapid pace, which still seems to be accelerating instead of slowing down. Therefore, both researchers and clinicians are constantly faced with new pathophysiological concepts, new drugs and new therapeutic frontiers. The field of pulmonary hypertension is large and encompasses a broad range of diseases and conditions affecting hundreds of thousands...
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ژورنال
عنوان ژورنال: Pediatric Cardiology and Cardiac Surgery
سال: 2021
ISSN: ['0911-1794', '2187-2988']
DOI: https://doi.org/10.9794/jspccs.37.2