منابع مشابه
Neuroanatomy and neurophysiology of itch.
The specific pathway of "pure," histaminergic itch is traced from the mechano-insensitive nerve fibers in the skin to their central cortical projections. Neuropathic itch created at different levels of this anatomical pathway is reviewed. In this review the present author discusses damage to pruritoceptors in the skin, entrapment syndromes, damage to spinal ganglia, nerve root impingement, inju...
متن کاملNew aspects of itch pathophysiology: component analysis of atopic itch using the 'Eppendorf Itch Questionnaire'.
Itch represents a leading symptom in dermatological practice with many psychophysiological aspects. Instruments for qualitative registration of these central nervous factors and evaluation of therapeutic measures are still missing. We analyzed in detail the subjective itch sensation in 108 patients with acute atopic eczema with a new questionnaire developed in analogy to the McGill pain questio...
متن کاملItch itch with not a wink of sleep
KEY CLINICAL MESSAGE A 55-year-old man of dark complexion presented with multiple extensive swellings over the chest, right upper arm, and left shoulder for 10 years. Swellings were hyperpigmented, firm, and intensely pruritic especially over the chest region. The swellings progressed in size, extended, and developed satellite lesions over its 10 years history.
متن کاملItch: role of prostaglandins.
Prostaglandin E(1) lowers the threshold of human skin to histamine-evoked itching. Though histamine and other mediators may produce itching by a direct action, itching in inflamed skin can also be explained by a pharmacological synergism in which low concentrations of prostaglandins, which do not themselves cause itching, potentiate itching due to histamine and possibly other agents. Alteration...
متن کامل[clinical Neurophysiology].
Consultant B. SCHURCH (SWITZERLAND) Disclaimer: The views and opinions expressed in the chapter are those of the authors and do not represent the views or the policies of the US Food and Drug Administration.
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2013
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.b13-00435