Update on Project ′87

Opioid Peptides: An Update, 87

Possible involvementofendogenousopioids inhumoral immune responseshas been explored in the experimental animals. Opioid agonists likemorphine and leu-enkephalin significantly enhanced antigen-inducedhistamine release from the peritoneal mast cells of sensitised rats invitro; this was effectively antagonised by naloxone. Naloxone itselfinhibited antigen-induced histamine rele...

I-3: Human Y Chromosome Proteome Project 2012 Update

The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...

Update on the Pathfinder Project

We review highlights of our research on Pathfinder, a decision-theoretic expert system for hematopathology diagnosis. We have developed techniques for efficiently acquiring, representing, and reasoning with uncertain biomedical knowledge. Specifically, we have developed a methodology for coping with complex dependencies among findings and disease in pathology. The methodology includes an extens...

Cohort Profile Update: The Amirkola Health and Ageing Project (AHAP)

The original cohort study of AHAP started in 2011 on 1616 elderly residents of Amirkola, northern part of Iran near the Caspian Sea. The main goal of this study was to comprehensively evaluate the health of the elderly in the region with the emphasis on chronic diseases such as osteoporosis. The first cohort profile was published in the International Journal of Epidemiology in 2014. The phase 1...

An update on the SOMax project