Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane
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منابع مشابه
Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane
ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor trafficking to the plasma membrane, we employed total internal reflection fluorescence (TIRF) micr...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2011
ISSN: 1662-5102
DOI: 10.3389/fncel.2011.00027